Author conclusion: It is important to note that there is insufficient data from RCT to definitively determine the most effective agent for hand washing to prevent neonatal infections. While there is a substantial amount of data from moderate to very low evidence research that suggests the superiority of one form of antiseptic hand hygiene agent over others to prevent neonatal infection this research is not as rigorous as a RCT’s. Consideration should be given to the fact that actual hand-washing techniques, particularly the seven-step and five-moment washing methods, were not measured in RCT research. The author concluded that the available RCT research did not provide sufficient data to make a statement about the best hand hygiene agent or method. The researchers concluded that more well-designed randomized controlled trials are needed to assess how hand hygiene and agent used can prevent noninvasive and invasive infections.